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Sickle cell anaemia is:
Options
(a) caused by substitution of valine by glutamic acids in the beta globin chain of heamoglobin
(b) caused by change in single base pair of DNA
(c) characterised by elongatd sickle like RBCs witha nucleus
(d) an autosomal linked dominant trait
Correct Answer:
caused by change in single base pair of DNA
Explanation:
Sickle cell anaemia is caused by a change in a single base pair of DNA. Sickle cell anaemia is the name of a specific form of sickle-cell disease in which there is homozygosity for the mutation that causes HbS. Sickle-cell disease, or sickle-cell anaemia (or drepanocytosis), is a life-long blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells flexibility and results in a risk of variouso complications.
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Topics: Genetics
(204)
Subject: Biology
(4253)
Important MCQs Based on Medical Entrance Examinations To Improve Your NEET Score
- Planaria possess high capacity of
- An example of synovial joint is found between
- The muscle fatigue occurs due to accumulation of
- Which one of the following help in absorption of phosphorus from soil by plants?
- Which one of the following expanded forms of the following acronyms is correct?
Topics: Genetics (204)
Subject: Biology (4253)
Important MCQs Based on Medical Entrance Examinations To Improve Your NEET Score
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