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Sickle cell anaemia is:
Options
(a) caused by substitution of valine by glutamic acids in the beta globin chain of heamoglobin
(b) caused by change in single base pair of DNA
(c) characterised by elongatd sickle like RBCs witha nucleus
(d) an autosomal linked dominant trait
Correct Answer:
caused by change in single base pair of DNA
Explanation:
Sickle cell anaemia is caused by a change in a single base pair of DNA. Sickle cell anaemia is the name of a specific form of sickle-cell disease in which there is homozygosity for the mutation that causes HbS. Sickle-cell disease, or sickle-cell anaemia (or drepanocytosis), is a life-long blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells flexibility and results in a risk of variouso complications.
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Topics: Genetics
(204)
Subject: Biology
(4253)
Important MCQs Based on Medical Entrance Examinations To Improve Your NEET Score
- Nerve impulse initiates with the movements of
- Select the option which is not correct with respect to enzyme action:
- Ligase is an enzyme required for
- Mesozoic era is the era of
- The macronutrient which is an essential component of all organic compounds
Topics: Genetics (204)
Subject: Biology (4253)
Important MCQs Based on Medical Entrance Examinations To Improve Your NEET Score
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