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Sickle cell anaemia is:
Options
(a) caused by substitution of valine by glutamic acids in the beta globin chain of heamoglobin
(b) caused by change in single base pair of DNA
(c) characterised by elongatd sickle like RBCs witha nucleus
(d) an autosomal linked dominant trait
Correct Answer:
caused by change in single base pair of DNA
Explanation:
Sickle cell anaemia is caused by a change in a single base pair of DNA. Sickle cell anaemia is the name of a specific form of sickle-cell disease in which there is homozygosity for the mutation that causes HbS. Sickle-cell disease, or sickle-cell anaemia (or drepanocytosis), is a life-long blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells flexibility and results in a risk of variouso complications.
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Topics: Genetics
(204)
Subject: Biology
(4253)
Important MCQs Based on Medical Entrance Examinations To Improve Your NEET Score
- Organisms which are indicator of SO2 pollution of air
- What is the first derived product of pyruvic acid after it enters into mitochondria
- To which type of barriers under innate immunity, do the saliva in the mouth
- F particles present in mitochondria are known as
- In which form does the food transported in plants
Topics: Genetics (204)
Subject: Biology (4253)
Important MCQs Based on Medical Entrance Examinations To Improve Your NEET Score
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