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Sickle cell anaemia is:
Options
(a) caused by substitution of valine by glutamic acids in the beta globin chain of heamoglobin
(b) caused by change in single base pair of DNA
(c) characterised by elongatd sickle like RBCs witha nucleus
(d) an autosomal linked dominant trait
Correct Answer:
caused by change in single base pair of DNA
Explanation:
Sickle cell anaemia is caused by a change in a single base pair of DNA. Sickle cell anaemia is the name of a specific form of sickle-cell disease in which there is homozygosity for the mutation that causes HbS. Sickle-cell disease, or sickle-cell anaemia (or drepanocytosis), is a life-long blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells flexibility and results in a risk of variouso complications.
Related Questions: - Which of the following pairs of animals has non glandular skin
- Restriction endonuclease is employed for cutting
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Topics: Genetics
(204)
Subject: Biology
(4253)
Important MCQs Based on Medical Entrance Examinations To Improve Your NEET Score
- Which of the following pairs of animals has non glandular skin
- Restriction endonuclease is employed for cutting
- Emasculation means
- Formation of liquid endosperm in coconut takes place because
- Frequency of Down’s syndrome increase when the maternal age is
Topics: Genetics (204)
Subject: Biology (4253)
Important MCQs Based on Medical Entrance Examinations To Improve Your NEET Score
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