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Anaphase Promoting ComplexAPC is a protein degradation machinery necessary

Anaphase Promoting Complex(APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC us defective in a human cell, which of the following is expected to occur?

Options

(a) Recombination of chromosome arms will occur
(b) Chromosomes will not condense
(c) Chromosomes will be fragmented
(d) Chromosomes will not segregate

Correct Answer:

Chromosomes will not segregate

Explanation:

Anaphase Promoting Complex (APC) is a protein necessary for separation of daughter chromosomes during anaphase. If APC is defective then the chromosomes will fail to segregate during anaphase.

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