Which of the following hormones can play a significant role in osteoporosis?

Options

(a) Parathyroid hormone and Prolactin
(b) Estrogen and Parathyroid hormone
(c) Progesterone and Aldosterone
(d) Aldosterone and Prolactin

Correct Answer:

Estrogen and Parathyroid hormone

Explanation:

Estrogen promotes the activity of osteoblast and inhibits osteoclast. In an ageing female osteoporosis occurs due to deficiency of estrogen. Parathormone promotes mobilisation of calcium from bone into blood. Excessive activity of parathormone causes demineralisation leading to osteoporosis.