The okazaki fragments in DNA chain growth

Options

(a) polymerize in the 3′-to-5′ direction and forms replication fork
(b) prove semi-conservative nature of DNA replication
(c) polymerize in the ‘5-to-3′ direction and explain 3′-to-5’ DNA replication
(d) result in transcription

Correct Answer:

polymerize in the ‘5-to-3′ direction and explain 3′-to-5’ DNA replication

Explanation:

Okazaki fragments in DNA are linked up by the enzyme DNA ligase. Replication alays ocur in 5′ – 3′ direction. Okazaki fragments synthesised on 3′ – 5′ DNA template, join to form lagging strand which grows in 3′ – 5′ direction.