Select the option which is not correct with respect to enzyme action:

Options

(a) Substrate binds with enzyme at its active site.
(b) Addition of lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate
(c) A non- competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate
(d) Malonate is a competitive inhibitor of succinic dehydrogenase

Correct Answer:

Addition of lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate

Explanation:

Inhibitions of succinic dehydrogenase by malonate is an example of competitive inhibition. Thus it is reversible reaction. On increasing the substrate (succinate) concentration the effect of inhibitor is removed Vmax remain same.