In sickel-cell anaemia, which of the following amino acids is substituted?

In sickel-cell anaemia, which of the following amino acids is substituted?

Options

(a) glutamic acid by valine in α-chain
(b) glutamic acid by valine in β-chain
(c) valine by glutamic acid in α-chain
(d) valine by glutamic acid in β-chain

Correct Answer:

glutamic acid by valine in β-chain

Explanation:

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