Gout is a disease that affects the joints and leads to arthritis. It is associated with an abnormality of

Options

(a) Pyrimidine metabolism
(b) Purine metabolism
(c) Fat metabolism
(d) Protein metabolism

Correct Answer:

Purine metabolism

Explanation:

Gout is a metabolic disorder, characterized by recurrent attack of arthritis, urate deposits in joints, kidney and other tissues, and elevated level of uric acid in blood and urine. The joint most commonly affected is great toe. Gout is an inherited disorder of purine metabolism, occurring, especially in men. Occurrence of gout is related to diet. Persons sufferings from gout should avoid meat which are a rich source of nucleic acid including purine.