Alzheimer disease in humans is associated with the deficiency of:
Options
(a) glutamic acid
(b) acetylcholine
(c) gamma aminobutyric acid (GABA)
(d) dopamine
Correct Answer:
acetylcholine
Explanation:
Alzheimer disease in humans is associated with the deficiency of acetylcholine. Acetylcholine is the neurotransmitter produced by neurons referred to as cholinergic neurons. Acetylcholine plays a role in skeletal muscle movement, as well as in the regulation of smooth muscle and cardiac muscle. Acetylcholine is synthesized from choline and acetyl coenzyme-A through the action of the enezyme choline acetyltransferase and becomes packaged into membrane bound vesicles.